Health Technology/clinical-trials

Landmark AI-Imaging Study Targets Non-Invasive Diagnosis of IBD and Intestinal TB — 5,000-Patient Trial Opens

247 Health News Editorial

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11 Apr 2026

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4 min read

·clinical-trials

A landmark 5,000-patient study is developing AI-enhanced imaging to non-invasively diagnose IBD, intestinal tuberculosis, and Behçet's disease. This could revolutionise gastroenterology by reducing reliance on invasive endoscopic procedures.

Originally reported by ClinicalTrials.gov

References

  1. 1.First Affiliated Hospital, Sun Yat-Sen University. (2024). AI-Driven Multimodal Imaging Integration for Diagnosis and Prognostication of Digestive System Diseases. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07087418
  2. 2.Maaser, C., Sturm, A., Vavricka, S. R., Kucharzik, T., Fiorino, G., Annese, V., Calabrese, E., Baumgart, D. C., Bettenworth, D., Borralho Nunes, P., Burisch, J., Castiglione, F., Eliakim, R., Franke, A., Gionchetti, P., Halligan, S., Katsanos, K., Kiudelis, G., Langhorst, J., ... Rimola, J. (2019). ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 1: Initial diagnosis, monitoring of known IBD, detection of complications. Journal of Crohn's and Colitis, 13(2), 144-164. https://doi.org/10.1093/ecco-jcc/jjy113
  3. 3.Liu, X., Faes, L., Kale, A. U., Wagner, S. K., Fu, D. J., Bruynseels, A., Mahendiran, T., Moraes, G., Shamdas, M., Kern, C., Ledsam, J. R., Schmid, M. K., Balaskas, K., Topol, E. J., Bachmann, L. M., Keane, P. A., & Denniston, A. K. (2019). A comparison of deep learning performance against health-care professionals in detecting diseases from medical imaging. The Lancet Digital Health, 1(6), e271-e297. https://doi.org/10.1016/S2589-7500(19)30123-2
  4. 4.Rimola, J., Rodriguez, S., García-Bosch, O., Ordás, I., Ayala, E., Aceituno, M., Pellisé, M., Ayuso, C., Ricart, E., Donoso, L., & Panés, J. (2009). Magnetic resonance for assessment of disease activity and severity in ileocolonic Crohn's disease. Gut, 58(8), 1113-1120. https://doi.org/10.1136/gut.2008.167957
  5. 5.Kedia, S., Das, P., Madhusudhan, K. S., Dattagupta, S., Sharma, R., Sahni, P., Makharia, G., & Ahuja, V. (2019). Differentiating Crohn's disease from intestinal tuberculosis. World Journal of Gastroenterology, 25(4), 418-432. https://doi.org/10.3748/wjg.v25.i4.418
  6. 6.Topol, E. J. (2019). High-performance medicine: the convergence of human and artificial intelligence. Nature Medicine, 25(1), 44-56. https://doi.org/10.1038/s41591-018-0300-7
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247 Health News Editorial

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