Health Technology/clinical-trials

Landmark 10,000-Patient Study Launches: Comprehensive Risk Prediction Model for Upper GI Cancers Using Endoscopy, Genetics, and Microbiota Data

247 Health News Editorial

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31 May 2026

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4 min read

·clinical-trials

A landmark 10,000-patient study will develop comprehensive risk prediction models for upper digestive tract cancers using endoscopy, genetics, and microbiota data. The six-year prospective cohort study aims to revolutionize screening strategies for gastric and esophageal cancers.

Originally reported by ClinicalTrials.gov

References

  1. 1.National Taiwan University Hospital. (2024). Development of Artificial Intelligence Risk Prediction Model for Upper Digestive Tract Cancer Using High Resolution Endoscopic Image, Digital Pathology, Genetics, and Oro-gastro-intestinal Microbiota. ClinicalTrials.gov. NCT07605312. https://clinicaltrials.gov/study/NCT07605312
  2. 2.Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71(3), 209-249. https://doi.org/10.3322/caac.21660
  3. 3.Smyth, E. C., Nilsson, M., Grabsch, H. I., van Grieken, N. C., & Lordick, F. (2020). Gastric cancer. The Lancet, 396(10251), 635-648. https://doi.org/10.1016/S0140-6736(20)31288-5
  4. 4.Pimentel-Nunes, P., Libânio, D., Marcos-Pinto, R., Areia, M., Leja, M., Esposito, G., ... & Dinis-Ribeiro, M. (2019). Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019. Endoscopy, 51(4), 365-388. https://doi.org/10.1055/a-1859-8803
  5. 5.Correa, P., & Piazuelo, M. B. (2012). The gastric precancerous cascade. Journal of Digestive Diseases, 13(1), 2-9. https://doi.org/10.1111/j.1751-2980.2011.00550.x
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