Landmark 10,000-Patient Cohort Study Tracks Long-Term Health Outcomes in ART Newborns — 30-Year Follow-Up Data to Guide Clinical Practice
247 Health News Editorial
·12 June 2026
·4 min read
·clinical-trialsA landmark 30-year prospective cohort study tracking 10,000 ART newborns will provide critical long-term safety data for assisted reproductive technologies. The study monitors birth outcomes and developmental health through 2050.
Originally reported by ClinicalTrials.gov
References
- 1.Australian Institute of Health and Welfare. (2023). Assisted reproductive technology in Australia and New Zealand 2021. AIHW. https://www.aihw.gov.au/reports/mothers-babies/assisted-reproductive-technology-australia-new-zealand
- 2.Berntsen, S., Söderström-Anttila, V., Wennerholm, U. B., Laivuori, H., Loft, A., Oldereid, N. B., Romundstad, L. B., Bergh, C., & Pinborg, A. (2019). The health of children conceived by ART: 'the chicken or the egg?' Human Reproduction Update, 25(2), 137-158. https://doi.org/10.1093/humupd/dmz001
- 3.European Society of Human Reproduction and Embryology. (2023). ART fact sheet. ESHRE Website. https://www.eshre.eu/Press-Room/Resources
- 4.First Affiliated Hospital of Zhengzhou University. (2019). Prospective Cohort Study for Newborns From Patients Treated With ART in Clinical Reproductive Medicine Management System/Electronic Medical Record Cohort Database (CCRM/EMRCD). ClinicalTrials.gov. NCT03993158. https://clinicaltrials.gov/study/NCT03993158
- 5.Hart, R., & Norman, R. J. (2013). The longer-term health outcomes for children born as a result of IVF treatment: Part I--General health outcomes. Human Reproduction Update, 19(3), 232-243. https://doi.org/10.1093/humupd/dms062
- 6.Pinborg, A., Wennerholm, U. B., Romundstad, L. B., Loft, A., Aittomaki, K., Söderström-Anttila, V., Nygren, K. G., Hazekamp, J., & Bergh, C. (2013). Why do singletons conceived after assisted reproduction technology have adverse perinatal outcome? Systematic review and meta-analysis. Human Reproduction Update, 19(2), 87-104. https://doi.org/10.1093/humupd/dms044
- 7.Qin, J., Liu, X., Sheng, X., Wang, H., & Gao, S. (2016). Assisted reproductive technology and the risk of pregnancy-related complications and adverse pregnancy outcomes in singleton pregnancies: a meta-analysis of cohort studies. Fertility and Sterility, 105(1), 73-85.e1-6. https://doi.org/10.1016/j.fertnstert.2015.09.007
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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