Health Technology/clinical-trials

Landmark 10,000-Patient Cohort Study Tracks Long-Term Health Outcomes in ART Newborns — 30-Year Follow-Up Data to Guide Clinical Practice

247 Health News Editorial

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12 June 2026

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4 min read

·clinical-trials

A landmark 30-year prospective cohort study tracking 10,000 ART newborns will provide critical long-term safety data for assisted reproductive technologies. The study monitors birth outcomes and developmental health through 2050.

Originally reported by ClinicalTrials.gov

References

  1. 1.Australian Institute of Health and Welfare. (2023). Assisted reproductive technology in Australia and New Zealand 2021. AIHW. https://www.aihw.gov.au/reports/mothers-babies/assisted-reproductive-technology-australia-new-zealand
  2. 2.Berntsen, S., Söderström-Anttila, V., Wennerholm, U. B., Laivuori, H., Loft, A., Oldereid, N. B., Romundstad, L. B., Bergh, C., & Pinborg, A. (2019). The health of children conceived by ART: 'the chicken or the egg?' Human Reproduction Update, 25(2), 137-158. https://doi.org/10.1093/humupd/dmz001
  3. 3.European Society of Human Reproduction and Embryology. (2023). ART fact sheet. ESHRE Website. https://www.eshre.eu/Press-Room/Resources
  4. 4.First Affiliated Hospital of Zhengzhou University. (2019). Prospective Cohort Study for Newborns From Patients Treated With ART in Clinical Reproductive Medicine Management System/Electronic Medical Record Cohort Database (CCRM/EMRCD). ClinicalTrials.gov. NCT03993158. https://clinicaltrials.gov/study/NCT03993158
  5. 5.Hart, R., & Norman, R. J. (2013). The longer-term health outcomes for children born as a result of IVF treatment: Part I--General health outcomes. Human Reproduction Update, 19(3), 232-243. https://doi.org/10.1093/humupd/dms062
  6. 6.Pinborg, A., Wennerholm, U. B., Romundstad, L. B., Loft, A., Aittomaki, K., Söderström-Anttila, V., Nygren, K. G., Hazekamp, J., & Bergh, C. (2013). Why do singletons conceived after assisted reproduction technology have adverse perinatal outcome? Systematic review and meta-analysis. Human Reproduction Update, 19(2), 87-104. https://doi.org/10.1093/humupd/dms044
  7. 7.Qin, J., Liu, X., Sheng, X., Wang, H., & Gao, S. (2016). Assisted reproductive technology and the risk of pregnancy-related complications and adverse pregnancy outcomes in singleton pregnancies: a meta-analysis of cohort studies. Fertility and Sterility, 105(1), 73-85.e1-6. https://doi.org/10.1016/j.fertnstert.2015.09.007
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247 Health News Editorial

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