Health Technology/clinical-trials

Hybrid Implementation Trial Tests Mobile Health vs Print Materials for HIV-Positive Smokers in Laos — Implementation Science Insights for Global Health

247 Health News Editorial

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19 Apr 2026

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4 min read

·clinical-trials

New hybrid implementation trial compares mobile health app versus print materials for smoking cessation in HIV-positive patients across 8 clinics in Laos. The study uses innovative Ask-Advise-Connect methodology to evaluate both effectiveness and real-world implementation outcomes.

Originally reported by ClinicalTrials.gov

References

  1. 1.University of Oklahoma. (2024). Implementing Sustainable Mobile Health Technology to Optimize Smoking Cessation Program for Lao People With HIV. ClinicalTrials.gov. NCT07014605. https://clinicaltrials.gov/study/NCT07014605
  2. 2.Curran, G. M., Bauer, M., Mittman, B., Pyne, J. M., & Stetler, C. (2012). Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact. Medical Care, 50(3), 217-226. https://doi.org/10.1097/MLR.0b013e3182408812
  3. 3.Feldstein, A. C., & Glasgow, R. E. (2008). A practical, robust implementation and sustainability model (PRISM) for integrating research findings into practice. Joint Commission Journal on Quality and Patient Safety, 34(4), 228-243. https://doi.org/10.1016/S1553-7250(08)34030-6
  4. 4.Hartmann-Boyce, J., Chepkin, S. C., Ye, W., Bullen, C., & Lancaster, T. (2018). Nicotine replacement therapy versus control for smoking cessation. Cochrane Database of Systematic Reviews, 5(5), CD000146. https://doi.org/10.1002/14651858.CD000146.pub5
  5. 5.Lifson, A. R., & Lando, H. A. (2012). Smoking and HIV: prevalence, health risks, and cessation strategies. Current HIV/AIDS Reports, 9(3), 223-230. https://doi.org/10.1007/s11904-012-0117-z
  6. 6.Whittaker, R., McRobbie, H., Bullen, C., Rodgers, A., & Gu, Y. (2016). Mobile phone-based interventions for smoking cessation. Cochrane Database of Systematic Reviews, 4(4), CD006611. https://doi.org/10.1002/14651858.CD006611.pub4
  7. 7.Vidrine, D. J., Shete, S., Cao, Y., Greisinger, A., Harmonson, P., Sharp, B., Miles, L., Zbikowski, S. M., & Wetter, D. W. (2013). Ask-Advise-Connect: a new approach to smoking treatment delivery in health care settings. JAMA Internal Medicine, 173(6), 458-464. https://doi.org/10.1001/jamainternmed.2013.3751
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247 Health News Editorial

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