Health Technology/clinical-trials

French Virtual Biopsy Trial Aims to Transform Glioma Grading Using Advanced MRI — What Australian Clinicians Need to Know

247 Health News Editorial

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13 May 2026

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4 min read

·clinical-trials

French researchers are developing virtual biopsy technology using advanced MRI to determine glioma grade without invasive tissue sampling. The 500-patient study could revolutionise brain tumour diagnosis by eliminating surgical risks while maintaining diagnostic accuracy.

Originally reported by ClinicalTrials.gov

References

  1. 1.Poitiers University Hospital. (2024). Virtual Biopsy Development to Identify Patient's Glioma Grade at the CHU of Poitiers Using Magnetic Resonance Imaging. ClinicalTrials.gov. NCT04313140. https://clinicaltrials.gov/study/NCT04313140
  2. 2.Ostrom, Q. T., Patil, N., Cioffi, G., Waite, K., Kruchko, C., & Barnholtz-Sloan, J. S. (2020). CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2013-2017. Neuro-Oncology, 22(12_Supplement_2), iv1-iv96. https://doi.org/10.1093/neuonc/noaa200
  3. 3.McGirt, M. J., Villavicencio, A. T., Bulsara, K. R., & Friedman, A. H. (2003). MRI-guided stereotactic biopsy in the diagnosis of glioma: comparison of biopsy and surgical resection specimen. Surgical Neurology, 59(4), 277-281. https://doi.org/10.1016/S0090-3019(03)00185-0
  4. 4.Louis, D. N., Perry, A., Wesseling, P., Brat, D. J., Cree, I. A., Figarella-Branger, D., ... & Ellison, D. W. (2021). The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro-Oncology, 23(8), 1231-1251. https://doi.org/10.1093/neuonc/noab106
  5. 5.Weller, M., van den Bent, M., Preusser, M., Le Rhun, E., Tonn, J. C., Minniti, G., ... & European Association for Neuro-Oncology (EANO) Task Force on Gliomas. (2021). EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood. Nature Reviews Clinical Oncology, 18(3), 170-186. https://doi.org/10.1038/s41571-021-00517-x
  6. 6.Bernstein, M., & Parrent, A. G. (1994). Complications of CT-guided stereotactic biopsy of intra-axial brain lesions. Journal of Neurosurgery, 81(2), 165-168. https://doi.org/10.3171/jns.1994.81.2.0165
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