FITWISE Trial Opens: Technology-Enhanced Home Exercise vs Standard Care in Pre-frail Older Adults — Singapore Pilot Study
247 Health News Editorial
·11 Apr 2026
·4 min read
·clinical-trialsThe FITWISE pilot trial evaluates a novel caregiver-mediated, technology-enhanced home exercise program for pre-frail older adults in Singapore. This three-arm study compares exergaming interventions with psychosocial support against standard care, targeting inactive community-dwelling adults aged 60-99 years.
Originally reported by ClinicalTrials.gov
References
- 1.Apóstolo, J., Cooke, R., Bobrowicz-Campos, E., Santana, S., Marcucci, M., Cano, A., Vollenbroek-Hutten, M., Germini, F., D'Avanzo, B., Gwyther, H., & Holland, C. (2018). Effectiveness of interventions to prevent pre-frailty and frailty progression in older adults: A systematic review. JBI Database of Systematic Reviews and Implementation Reports, 16(1), 140-232. https://doi.org/10.11124/JBISRIR-2017-003382
- 2.Cesari, M., Araujo de Carvalho, I., Amuthavalli Thiyagarajan, J., Cooper, C., Martin, F. C., Reginster, J. Y., Vellas, B., & Beard, J. R. (2018). Evidence for the domains supporting the construct of intrinsic capacity. The Journals of Gerontology Series A, 73(10), 1653-1660. https://doi.org/10.1093/gerona/gly011
- 3.Clegg, A., Young, J., Iliffe, S., Rikkert, M. O., & Rockwood, K. (2013). Frailty in elderly people. The Lancet, 381(9868), 752-762. https://doi.org/10.1016/S0140-6736(12)62167-9
- 4.Gitlin, L. N., Hodgson, N., Jutkowitz, E., & Pizzi, L. (2010). The cost-effectiveness of a nonpharmacologic intervention for individuals with dementia and family caregivers: The tailored activity program. American Journal of Geriatric Psychiatry, 18(6), 510-519. https://doi.org/10.1097/JGP.0b013e3181d5f9db
- 5.Merchant, R. A., Chen, M. Z., Tan, L. W. L., Lim, M. Y., Ho, H. K., & van Dam, R. M. (2017). Singapore Healthy Older People Everyday (HOPE) Study: Prevalence of frailty and associated factors in older adults. Journal of the American Medical Directors Association, 18(8), 734.e9-734.e14. https://doi.org/10.1016/j.jamda.2016.09.017
- 6.Molina, K. I., Ricci, N. A., de Moraes, S. A., & Perracini, M. R. (2014). Virtual reality using games for improving physical functioning in older adults: A systematic review. Journal of NeuroEngineering and Rehabilitation, 11, 156. https://doi.org/10.1186/1743-0003-11-156
- 7.National University of Singapore. (2024). The Development and Feasibility Testing of a Caregiver-mediated, Technology-facilitated, Home-based Frail Intervention Program (FITWISE) for Pre-frail and Frail Community-dwelling Older Adults: a Three-arm Pilot Randomized Controlled Trial. ClinicalTrials.gov. NCT07519642. https://clinicaltrials.gov/study/NCT07519642
- 8.Thabane, L., Ma, J., Chu, R., Cheng, J., Ismaila, A., Rios, L. P., Robson, R., Thabane, M., Giangregorio, L., & Goldsmith, C. H. (2010). A tutorial on pilot studies: The what, why and how. BMC Medical Research Methodology, 10, 1. https://doi.org/10.1186/1471-2288-10-1
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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