First Digital CBT Therapeutic Targets Mental Health Burden in Long COVID: Pilot Trial of Rauha® Platform Opens for Recruitment
247 Health News Editorial
·21 July 2026
·4 min read
·clinical-trialsA new pilot trial is evaluating the Rauha® Digital Therapeutic Platform (Toivoa-004) as a CBT-based digital intervention for Long COVID patients experiencing anxiety or depression. The 20-participant US feasibility study will assess 12-week engagement rates and early symptom change signals, potentially informing a future randomised trial in this underserved population.
Originally reported by ClinicalTrials.gov
References
- 1.Toivoa Inc. (2025). Development of an accessible cognitive behavioral therapy digital therapeutic for individuals with Long COVID (NCT07714889). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07714889
- 2.Thaweethai, T., Jolley, S. E., Karlson, E. W., Levitan, E. B., Levy, B., McComsey, G. A., McCorkell, L., Nadkarni, G. N., Parthasarathy, S., Singh, U., Walker, T. A., Weinstock, M. B., Whiteson, J. H., Zisis, S., & Horwitz, L. I. (2023). Development of a definition of postacute sequelae of SARS-CoV-2 infection. JAMA, 329(22), 1934–1946. https://doi.org/10.1001/jama.2023.8823
- 3.Linardon, J., & Fuller-Tyszkiewicz, M. (2020). Attrition and adherence in smartphone-delivered interventions for mental health problems: A systematic and meta-analytic review. Journal of Consulting and Clinical Psychology, 88(1), 1–13. https://doi.org/10.1037/ccp0000459
- 4.Taquet, M., Luciano, S., Geddes, J. R., & Harrison, P. J. (2021). Bidirectional associations between COVID-19 and psychiatric disorder: Retrospective cohort studies of 62 354 COVID-19 cases in the USA. The Lancet Psychiatry, 8(2), 130–140. https://doi.org/10.1016/S2215-0366(20)30462-4
- 5.Linardon, J., Cuijpers, P., Carlbring, P., Messer, M., & Fuller-Tyszkiewicz, M. (2019). The efficacy of app-supported smartphone interventions for mental health problems: A meta-analysis of randomized controlled trials. World Psychiatry, 18(3), 325–336. https://doi.org/10.1002/wps.20673
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247 Health News Editorial
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