Health Technology/clinical-trials

Feasibility RCT Launches: Email-Delivered Positive Affect Intervention vs Psychoeducation for Depression in Zimbabwean Young Adults — Key Details for Global Mental Health Clinicians

247 Health News Editorial

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24 July 2026

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4 min read

·clinical-trials

A new feasibility RCT from Vilnius University is testing a brief, email-delivered positive affect intervention against psychoeducational control in Zimbabwean young adults with moderate depression. The trial, enrolling 100 participants aged 18–25, aims to establish the recruitment, retention, and acceptability benchmarks needed to design a future definitive efficacy trial. For global mental health clinicians, the findings could help shape scalable digital intervention models for low-resource settings.

Originally reported by ClinicalTrials.gov

References

  1. 1.Vilnius University. (2025). A brief email-delivered positive affect intervention for young adults in Zimbabwe: A feasibility randomized controlled trial. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07682779
  2. 2.Fredrickson, B. L. (2001). The role of positive emotions in positive psychology: The broaden-and-build theory of positive emotions. American Psychologist, 56(3), 218–226. https://doi.org/10.1037/0003-066X.56.3.218
  3. 3.GBD 2019 Mental Disorders Collaborators. (2022). Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: A systematic analysis for the Global Burden of Disease Study 2019. The Lancet Psychiatry, 9(2), 137–150. https://doi.org/10.1016/S2215-0366(21)00395-3
  4. 4.Chisholm, D., Sweeny, K., Sheehan, P., Rasmussen, B., Smit, F., Cuijpers, P., & Saxena, S. (2016). Scaling-up treatment of depression and anxiety: A global return on investment analysis. The Lancet Psychiatry, 3(5), 415–424. https://doi.org/10.1016/S2215-0366(16)30024-4
  5. 5.Naslund, J. A., Aschbrenner, K. A., Araya, R., Marsch, L. A., Unützer, J., Patel, V., & Bartels, S. J. (2017). Digital technology for treating and preventing mental disorders in low-income and middle-income countries: A narrative review of the literature. The Lancet Psychiatry, 4(6), 486–500. https://doi.org/10.1016/S2215-0366(17)30096-2
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