EVAREST Study: Novel Blood and Imaging Biomarkers to Enhance Stress Echocardiography Accuracy in Coronary Disease — What Clinicians Need to Know
247 Health News Editorial
·4 May 2026
·3 min read
·clinical-trialsThe EVAREST study is investigating novel blood and imaging biomarkers to improve stress echocardiography accuracy in diagnosing coronary artery disease. This large UK-based observational study of 23,000 participants aims to reduce interpretation variability and enhance diagnostic confidence in cardiac assessment.
Originally reported by ClinicalTrials.gov
References
- 1.University of Oxford. (2018). Use of Imaging and Blood Biomarkers to Improve the Diagnostic Accuracy of Cardiac Assessment by Stress Echocardiogram. ClinicalTrials.gov. NCT03674255. https://clinicaltrials.gov/study/NCT03674255
- 2.Pellikka, P. A., Nagueh, S. F., Elhendy, A. A., Kuehl, C. A., & Sawada, S. G. (2007). American Society of Echocardiography recommendations for performance, interpretation, and application of stress echocardiography. Journal of the American Society of Echocardiography, 20(9), 1021-1041. https://doi.org/10.1016/j.echo.2007.07.003
- 3.Hoffmann, R., Lethen, H., Marwick, T., Arnese, M., Fioretti, P., Pingitore, A., ... & Hanrath, P. (1996). Analysis of interinstitutional observer agreement in interpretation of dobutamine stress echocardiograms. Journal of the American College of Cardiology, 27(2), 330-336. https://doi.org/10.1016/0735-1097(96)00055-5
- 4.Knuuti, J., Wijns, W., Saraste, A., Capodanno, D., Barbato, E., Funck-Brentano, C., ... & Windecker, S. (2020). 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. European Heart Journal, 41(3), 407-477. https://doi.org/10.1093/eurheartj/ehz425
- 5.Marwick, T. H. (2018). Stress echocardiography. Heart, 104(16), 1331-1338. https://doi.org/10.1136/heartjnl-2017-311682
- 6.Sicari, R., Nihoyannopoulos, P., Evangelista, A., Kasprzak, J., Lancellotti, P., Poldermans, D., ... & Zamorano, J. L. (2008). Stress echocardiography expert consensus statement. European Journal of Echocardiography, 9(4), 415-437. https://doi.org/10.1016/j.euje.2008.02.001
- 7.Australian Institute of Health and Welfare. (2023). Cardiovascular disease in Australia. AIHW. https://www.aihw.gov.au/reports/heart-stroke-vascular-diseases/cardiovascular-health-compendium
2
247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
Related Articles
clinical-trials
Digital Health Platform vs Case Manager Support in Hypertension Management: Taiwan's 1,726-Participant Trial Signals a Shift in Blood Pressure Care Delivery
3 Aug 2026
clinical-trials
Phase II Trial: AI-Powered Wysa Chatbot vs Unmet Need — Digital Eating Disorder Prevention in At-Risk Adolescents
3 Aug 2026
clinical-trials
Pilot Trial Targets the Inpatient-to-Outpatient Gap: Digital Smoking Cessation Intervention for Persons With Serious Mental Illness — Key Findings for Clinicians
3 Aug 2026
This content is for educational purposes for healthcare professionals only and does not constitute clinical advice. Clinical decisions should be based on individual patient assessment, current guidelines, and appropriate specialist consultation. Editorial Standards · Privacy Policy · Terms of Service