EMR-Integrated Platform Nest Targets the Surveillance Gap in Young Adults Carrying Hereditary Cancer Variants — Trial Details for Clinicians
247 Health News Editorial
·18 July 2026
·5 min read
·clinical-trialsA US-based clinical trial is evaluating Nest, an EMR-integrated platform designed to improve cancer surveillance adherence and reduce psychological distress in young adults carrying pathogenic hereditary cancer variants. Conducted at Dana-Farber Cancer Institute, the study targets a critical gap between genetic diagnosis and long-term clinical follow-through. Australian familial cancer clinicians should monitor outcomes as the model has direct relevance to local practice.
Originally reported by ClinicalTrials.gov
References
- 1.Nest Genomics. (2024). Enhancing information management for young adults after genetic cancer risk testing (NCT06654466). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT06654466
- 2.Childers, C. P., Childers, K. K., Maggard-Gibbons, M., & Macinko, J. (2017). National estimates of genetic testing in women with a history of breast or ovarian cancer. Journal of Clinical Oncology, 35(34), 3800–3806. https://doi.org/10.1200/JCO.2017.73.6314
- 3.Oliveri, S., Cincidda, C., Peiró, G., Renzi, C., & Pravettoni, G. (2021). What does distress mean for cancer patients? A qualitative study on the experience of distress and its relationship with quality of life. Frontiers in Psychology, 12, 644126. https://doi.org/10.3389/fpsyg.2021.644126
- 4.Bonadies, D. C., Moyer, A., Matloff, E. T., & Brierley, K. L. (2011). Implications of incomplete adherence to cancer surveillance recommendations in BRCA1/2 mutation carriers. Familial Cancer, 10(4), 745–751. https://doi.org/10.1007/s10689-011-9437-1
- 5.Robson, M. E., Bradbury, A. R., Arun, B., Domchek, S. M., Ford, J. M., Hampel, H. L., Lipkin, S. M., Syngal, S., Wollins, D. S., & Lindor, N. M. (2015). American Society of Clinical Oncology policy statement update: Genetic and genomic testing for cancer susceptibility. Journal of Clinical Oncology, 33(31), 3660–3667. https://doi.org/10.1200/JCO.2015.63.0996
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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