EMPOWER Trial Opens: Digital ExerciseRx™ Platform vs. Health Education in Non-Muscle Invasive Bladder Cancer — Can a Smartphone App Close the Physical Activity Gap?
247 Health News Editorial
·24 July 2026
·5 min read
·clinical-trialsThe EMPOWER Trial (NCT07302230) is now recruiting patients with non-muscle invasive bladder cancer to evaluate whether the ExerciseRx™ digital platform can increase physical activity more effectively than health education alone. With NMIBC representing the majority of bladder cancer diagnoses and physical inactivity a modifiable mortality risk, this University of Washington-led study could reshape survivorship care pathways for a chronically undertreated population.
Originally reported by ClinicalTrials.gov
References
- 1.University of Washington. (2025). The EMPOWER trial: Evaluating a home-based physical activity program (PAP) with the ExerciseRx™ digital platform vs. health education group (HEG) in people with non-muscle invasive bladder cancer (NCT07302230). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07302230
- 2.Siegel, R. L., Miller, K. D., Wagle, N. S., & Jemal, A. (2023). Cancer statistics, 2023. CA: A Cancer Journal for Clinicians, 73(1), 17–48. https://doi.org/10.3322/caac.21763
- 3.Babjuk, M., Burger, M., Capoun, O., Cohen, D., Compérat, E. M., Dominguez Escrig, J. L., Gontero, P., Liedberg, F., Masson-Lecomte, A., Mostafid, A. H., Palou, J., van Rhijn, B. W. G., Rouprêt, M., Shariat, S. F., Seisen, T., Soukup, V., & Sylvester, R. J. (2022). European Association of Urology guidelines on non-muscle-invasive bladder cancer (Ta, T1, and carcinoma in situ). European Urology, 81(1), 75–94. https://doi.org/10.1016/j.eururo.2021.08.010
- 4.Coleman, K. J., Ngor, E., Reynolds, K., Quinn, V. P., Koebnick, C., Young, D. R., Sternfeld, B., & Sallis, R. E. (2012). Initial validation of an exercise 'vital sign' in electronic medical records. Medicine & Science in Sports & Exercise, 44(11), 2071–2076. https://doi.org/10.1249/MSS.0b013e3182630ec1
- 5.Buffart, L. M., Galvão, D. A., Brug, J., Chinapaw, M. J. M., & Newton, R. U. (2014). Evidence-based physical activity guidelines for cancer survivors: Current guidelines, knowledge gaps and future research directions. Cancer Treatment Reviews, 40(2), 327–340. https://doi.org/10.1016/j.ctrv.2013.11.007
- 6.Patel, A. V., Friedenreich, C. M., Moore, S. C., Hayes, S. C., Silver, J. K., Campbell, K. L., Winters-Stone, K., Gerber, L. H., George, S. M., Fulton, J. E., Denlinger, C., Morris, G. S., Hue, T., Schmitz, K. H., & Matthews, C. E. (2019). American College of Sports Medicine roundtable report on physical activity, sedentary behavior, and cancer prevention and control. Medicine & Science in Sports & Exercise, 51(11), 2391–2402. https://doi.org/10.1249/MSS.0000000000002117
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247 Health News Editorial
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