Digital Biomarkers Study Opens: Wearable Technology to Monitor Motor Function in PSP and Lewy Body Dementia — Validation for Clinical Trials
247 Health News Editorial
·11 Apr 2026
·4 min read
·clinical-trialsNew validation study explores wearable technology for monitoring motor function in progressive supranuclear palsy and Lewy body dementia. Could revolutionise clinical trials and patient care through objective digital biomarkers.
Originally reported by ClinicalTrials.gov
References
- 1.BioSensics. (2024). Digital Health Technologies For Monitoring Disease Symptoms in Progressive Supranuclear Palsy and Dementia With Lewy Bodies. ClinicalTrials.gov. NCT07240805. https://clinicaltrials.gov/study/NCT07240805
- 2.Bonanni, L., Thomas, A., Tiraboschi, P., Perfetti, B., Varanese, S., & Onofrj, M. (2008). EEG comparisons in early Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease with dementia. Brain, 131(9), 2353-2363. https://doi.org/10.1093/brain/awm322
- 3.Dorsey, E. R., Papapetropoulos, S., Xiong, M., & Kieburtz, K. (2017). The first frontier: digital biomarkers for neurodegenerative disorders. Digital Biomarkers, 1(1), 6-13. https://doi.org/10.1159/000477383
- 4.Goldsack, J. C., Coravos, A., Bakker, J. P., Bent, B., Dowling, A. V., Fitzer-Attas, C., Godfrey, A., Godino, J. G., Gujar, N., Izmailova, E., Manta, C., Peterson, B., Vandendriessche, B., Wood, W. A., Wang, K. W., & Dunn, J. (2020). Verification, analytical validation, and clinical validation (V3): the foundation of determining fit-for-purpose for Biometric Monitoring Technologies (BioMeTs). npj Digital Medicine, 3(1), 55. https://doi.org/10.1038/s41746-020-0260-4
- 5.Höglinger, G. U., Respondek, G., Stamelou, M., Kurz, C., Josephs, K. A., Lang, A. E., Mollenhauer, B., Müller, U., Nilsson, C., Whitwell, J. L., Arzberger, T., Englund, E., Gelpi, E., Giese, A., Irwin, D. J., Meissner, W. G., Pantelyat, A., Rajput, A., van Swieten, J. C., ... Movement Disorder Society-endorsed PSP Study Group. (2017). Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria. Movement Disorders, 32(6), 853-864. https://doi.org/10.1002/mds.26987
- 6.Maetzler, W., Domingos, J., Srulijes, K., Ferreira, J. J., & Bloem, B. R. (2013). Quantitative wearable sensors for objective assessment of Parkinson's disease. Movement Disorders, 28(12), 1628-1637. https://doi.org/10.1002/mds.25628
- 7.McKeith, I. G., Boeve, B. F., Dickson, D. W., Halliday, G., Taylor, J. P., Weintraub, D., Aarsland, D., Galvin, J., Attems, J., Ballard, C. G., Bayston, A., Beach, T. G., Blanc, F., Bohnen, N., Bonanni, L., Bras, J., Brundin, P., Burn, D., Chen-Plotkin, A., ... Kosaka, K. (2017). Diagnosis and management of dementia with Lewy bodies: fourth consensus report of the DLB Consortium. Neurology, 89(1), 88-100. https://doi.org/10.1212/WNL.0000000000004058
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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