Health Technology/clinical-trials

DELINEATE-Prospective Trial: AI-Assisted Echocardiography Analysis for Valvular Heart Disease — Real-World Clinical Impact Study

247 Health News Editorial

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17 Apr 2026

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4 min read

·clinical-trials

The DELINEATE-Prospective trial evaluates real-time AI assistance for echocardiographic interpretation of valvular heart disease. This Columbia University study tests whether artificial intelligence can improve diagnostic accuracy and reduce inter-observer variability in routine cardiology practice.

Originally reported by ClinicalTrials.gov

References

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  2. 2.Columbia University. (2024). Deep Learning for Echo Analysis, Tracking, and Evaluation Prospective Evaluation (DELINEATE-Prospective). ClinicalTrials.gov. NCT07197736. https://clinicaltrials.gov/study/NCT07197736
  3. 3.Evangelista, A., Tornos, P., Sambola, A., Permanyer-Miralda, G., & Soler-Soler, J. (1999). Quantification of mitral regurgitation by Doppler echocardiography. American Heart Journal, 138(5), 1026-1031. https://doi.org/10.1016/S0002-8703(99)70315-4
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  5. 5.Nkomo, V. T., Gardin, J. M., Skelton, T. N., Gottdiener, J. S., Scott, C. G., & Enriquez-Sarano, M. (2006). Burden of valvular heart diseases: a population-based study. The Lancet, 368(9540), 1005-1011. https://doi.org/10.1016/S0140-6736(06)69208-8
  6. 6.Ouyang, D., He, B., Ghorbani, A., Yuan, N., Ebinger, J., Langlotz, C. P., ... & Zou, J. Y. (2020). Video-based AI for beat-to-beat assessment of cardiac function. Nature, 580(7802), 252-256. https://doi.org/10.1038/s41586-020-2145-8
  7. 7.Popescu, B. A., Andrade, M. J., Badano, L. P., Fox, K. F., Flachskampf, F. A., Lancellotti, P., ... & Zamorano, J. L. (2016). European Association of Echocardiography recommendations for training, competence, and quality improvement in echocardiography. European Heart Journal Cardiovascular Imaging, 17(10), 1115-1128. https://doi.org/10.1093/ehjci/jew125
  8. 8.Vahanian, A., Beyersdorf, F., Praz, F., Milojevic, M., Baldus, S., Bauersachs, J., ... & ESC/EACTS Scientific Document Group. (2022). 2021 ESC/EACTS Guidelines for the management of valvular heart disease. European Heart Journal, 43(7), 561-632. https://doi.org/10.1093/eurheartj/ehab395
  9. 9.Zhang, J., Gajjala, S., Agrawal, P., Tison, G. H., Hallock, L. A., Beussink-Nelson, L., ... & Shah, S. J. (2018). Fully automated echocardiogram interpretation in clinical practice. Circulation, 138(16), 1623-1635. https://doi.org/10.1161/CIRCULATIONAHA.118.034338
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