Completed Trial Tests Machine Learning Bolus Enhancement for Automated Insulin Delivery in Type 1 Diabetes
247 Health News Editorial
·13 June 2026
·3 min read
·clinical-trialsA completed crossover trial tested whether adding machine learning-enhanced bolus priming to automated insulin delivery systems could improve time in range for adults with type 1 diabetes. Results from this 19-participant study could inform the next generation of artificial pancreas technology.
Originally reported by ClinicalTrials.gov
References
- 1.Beck, R. W., Bergenstal, R. M., Cheng, P., Kollman, C., Laffel, L. M., Li, Z., ... & Xing, D. (2019). The relationships between time in range, hyperglycemia metrics, and HbA1c. Journal of Diabetes Science and Technology, 13(4), 614-626. https://doi.org/10.1177/1932296818822496
- 2.Bekiari, E., Kitsios, K., Thabit, H., Tauschmann, M., Athanasiadou, E., Karagiannis, T., ... & Tsapas, A. (2018). Artificial pancreas treatment for outpatients with type 1 diabetes: systematic review and meta-analysis. BMJ, 361, k1310. https://doi.org/10.1136/bmj.k1310
- 3.Boughton, C. K., & Hovorka, R. (2021). Advances in artificial pancreas systems. Science Translational Medicine, 13(599), eabg6279. https://doi.org/10.1126/scitranslmed.abg6279
- 4.Brown, S. (2024). Safety and Feasibility of a Machine-Learning Bolus Priming Added to Existing Control Algorithm. ClinicalTrials.gov Identifier: NCT06728059. https://clinicaltrials.gov/study/NCT06728059
- 5.Brown, S. A., Kovatchev, B. P., Raghinaru, D., Lum, J. W., Buckingham, B. A., Kudva, Y. C., ... & Dassau, E. (2019). Six-month randomized, multicenter trial of closed-loop control in type 1 diabetes. New England Journal of Medicine, 381(15), 1707-1717. https://doi.org/10.1056/NEJMoa1907863
- 6.Sherr, J. L., Tauschmann, M., Battelino, T., de Bock, M., Forlenza, G., Roman, R., ... & Maahs, D. M. (2018). ISPAD Clinical Practice Consensus Guidelines 2018: Diabetes technologies. Pediatric Diabetes, 19(S27), 302-325. https://doi.org/10.1111/pedi.12731
- 7.Tauschmann, M., & Hovorka, R. (2018). Technology in the management of type 1 diabetes mellitus—current status and future prospects. Nature Reviews Endocrinology, 14(8), 464-475. https://doi.org/10.1038/nrendo.2018.31
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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