Health Technology/clinical-trials

Completed Trial: Telehealth Exercise Intervention Shows Promise for Childhood Cancer Survivors with Exercise Intolerance — Key Findings for Oncology and Rehabilitation Teams

247 Health News Editorial

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4 Apr 2026

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3 min read

·clinical-trials

A completed randomised trial of 181 young adult childhood cancer survivors tested whether individually tailored, telehealth-delivered exercise programs could improve functional capacity in those with exercise intolerance. Results pending publication could inform survivorship care protocols globally.

Originally reported by ClinicalTrials.gov

References

  1. 1.St. Jude Children's Research Hospital. (2024). Telehealth Based Intervention to Improve Functional Capacity in Survivors of Childhood Cancer With Significantly Limited Exercise Tolerance. ClinicalTrials.gov. NCT04714840. https://clinicaltrials.gov/study/NCT04714840
  2. 2.Hudson, M. M., Ness, K. K., Gurney, J. G., Mulrooney, D. A., Chemaitilly, W., Krull, K. R., Green, D. M., Armstrong, G. T., Nottage, K. A., Jones, K. E., Sklar, C. A., Srivastava, D. K., & Robison, L. L. (2013). Clinical ascertainment of health outcomes among adults treated for childhood cancer. JAMA, 309(22), 2371-2381. https://doi.org/10.1001/jama.2013.280519
  3. 3.Ness, K. K., Armenian, S. H., Kadan‐Lottick, N., & Gurney, J. G. (2011). Adverse effects of treatment in childhood acute lymphoblastic leukemia: general overview and implications for long‐term cardiac health. Expert Review of Hematology, 4(2), 185-197. https://doi.org/10.1586/ehm.11.8
  4. 4.Morales, J. S., Valenzuela, P. L., Rincón‐Castanedo, C., Takken, T., Fiuza‐Luces, C., Santos‐Lozano, A., Ramírez, M., Oliván, J., & Lucia, A. (2018). Exercise training in childhood cancer: A systematic review and meta‐analysis of randomized controlled trials. Cancer Treatment Reviews, 70, 154-167. https://doi.org/10.1016/j.ctrv.2018.05.010
  5. 5.Mulrooney, D. A., Yeazel, M. W., Kawashima, T., Mertens, A. C., Mitby, P., Stovall, M., Donaldson, S. S., Green, D. M., Sklar, C. A., Robison, L. L., & Leisenring, W. M. (2009). Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: retrospective analysis of the Childhood Cancer Survivor Study cohort. BMJ, 339, b4606. https://doi.org/10.1136/bmj.b4606
  6. 6.Ness, K. K., Plana, J. C., Joshi, V. M., Luepker, R. V., Durand, J. B., Green, D. M., Partin, R. E., Santucci, A. K., Howell, R. M., Srivastava, D. K., Edelmann, M. N., Reddick, W. E., Robison, L. L., & Hudson, M. M. (2014). Exercise intolerance, mortality, and organ system impairment in adult survivors of childhood cancer. Journal of Clinical Oncology, 32(22), 2317-2327. https://doi.org/10.1200/JCO.2013.55.4847
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247 Health News Editorial

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