Completed Trial: Telehealth Exercise Intervention Shows Promise for Childhood Cancer Survivors with Exercise Intolerance — Key Findings for Oncology and Rehabilitation Teams
247 Health News Editorial
·4 Apr 2026
·3 min read
·clinical-trialsA completed randomised trial of 181 young adult childhood cancer survivors tested whether individually tailored, telehealth-delivered exercise programs could improve functional capacity in those with exercise intolerance. Results pending publication could inform survivorship care protocols globally.
Originally reported by ClinicalTrials.gov
References
- 1.St. Jude Children's Research Hospital. (2024). Telehealth Based Intervention to Improve Functional Capacity in Survivors of Childhood Cancer With Significantly Limited Exercise Tolerance. ClinicalTrials.gov. NCT04714840. https://clinicaltrials.gov/study/NCT04714840
- 2.Hudson, M. M., Ness, K. K., Gurney, J. G., Mulrooney, D. A., Chemaitilly, W., Krull, K. R., Green, D. M., Armstrong, G. T., Nottage, K. A., Jones, K. E., Sklar, C. A., Srivastava, D. K., & Robison, L. L. (2013). Clinical ascertainment of health outcomes among adults treated for childhood cancer. JAMA, 309(22), 2371-2381. https://doi.org/10.1001/jama.2013.280519
- 3.Ness, K. K., Armenian, S. H., Kadan‐Lottick, N., & Gurney, J. G. (2011). Adverse effects of treatment in childhood acute lymphoblastic leukemia: general overview and implications for long‐term cardiac health. Expert Review of Hematology, 4(2), 185-197. https://doi.org/10.1586/ehm.11.8
- 4.Morales, J. S., Valenzuela, P. L., Rincón‐Castanedo, C., Takken, T., Fiuza‐Luces, C., Santos‐Lozano, A., Ramírez, M., Oliván, J., & Lucia, A. (2018). Exercise training in childhood cancer: A systematic review and meta‐analysis of randomized controlled trials. Cancer Treatment Reviews, 70, 154-167. https://doi.org/10.1016/j.ctrv.2018.05.010
- 5.Mulrooney, D. A., Yeazel, M. W., Kawashima, T., Mertens, A. C., Mitby, P., Stovall, M., Donaldson, S. S., Green, D. M., Sklar, C. A., Robison, L. L., & Leisenring, W. M. (2009). Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: retrospective analysis of the Childhood Cancer Survivor Study cohort. BMJ, 339, b4606. https://doi.org/10.1136/bmj.b4606
- 6.Ness, K. K., Plana, J. C., Joshi, V. M., Luepker, R. V., Durand, J. B., Green, D. M., Partin, R. E., Santucci, A. K., Howell, R. M., Srivastava, D. K., Edelmann, M. N., Reddick, W. E., Robison, L. L., & Hudson, M. M. (2014). Exercise intolerance, mortality, and organ system impairment in adult survivors of childhood cancer. Journal of Clinical Oncology, 32(22), 2317-2327. https://doi.org/10.1200/JCO.2013.55.4847
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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