Health Technology/clinical-trials

Completed Trial: AI-Chatbot mHealth Intervention vs Standard Education for HIV Testing Uptake Among MSM in Malaysia — Key Findings for Clinicians

247 Health News Editorial

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18 July 2026

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5 min read

·clinical-trials

A completed Yale University-sponsored randomised trial has evaluated whether an AI-driven chatbot delivered via smartphone can increase HIV testing uptake among MSM in Malaysia compared to an attention-control chatbot and standard educational materials. With 307 participants enrolled and a 180-day testing endpoint, the findings are anticipated to inform digital HIV prevention strategies across Southeast Asia and beyond.

Originally reported by ClinicalTrials.gov

References

  1. 1.Yale University. (2022). Developing an artificial intelligence (AI)-based mHealth intervention to improve HIV testing in Malaysia (NCT05335096). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT05335096
  2. 2.Wirtz, A. L., Pretorius, C., Beyrer, C., Baral, S., Decker, M. R., Sherman, S. G., & Kerrigan, D. (2014). Epidemic impacts of a community empowerment intervention for HIV prevention among female sex workers in generalized and concentrated epidemics. PLOS ONE, 9(1), e83358. https://doi.org/10.1371/journal.pone.0083358
  3. 3.Muessig, K. E., Nekkanti, M., Bauermeister, J., Bull, S., & Hightow-Weidman, L. B. (2015). A systematic review of recent smartphone, Internet and Web 2.0 interventions to address the HIV continuum of care. Current HIV/AIDS Reports, 12(1), 173–190. https://doi.org/10.1007/s11904-014-0239-3
  4. 4.UNAIDS. (2023). The path that ends AIDS: UNAIDS global AIDS update 2023. UNAIDS. https://www.unaids.org/en/resources/documents/2023/global-aids-update-2023
  5. 5.Baral, S., Logie, C. H., Grosso, A., Wirtz, A. L., & Beyrer, C. (2013). Modified social ecological model: a tool to guide the assessment of the risks and risk contexts of HIV epidemics. BMC Public Health, 13, 482. https://doi.org/10.1186/1471-2458-13-482
  6. 6.Hightow-Weidman, L. B., & Muessig, K. E. (2018). The future of digital health interventions for HIV prevention and care. Current Opinion in HIV and AIDS, 13(5), 366–373. https://doi.org/10.1097/COH.0000000000000490
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