Health Technology/clinical-trials

Completed Study Reveals Lower Limb Strength Predicts Brain Oxygenation During Exercise — New Insights for Rehabilitation and Sports Medicine

247 Health News Editorial

·

14 May 2026

·

4 min read

·clinical-trials

Completed study of 256 participants reveals lower limb muscle strength can predict brain oxygenation patterns during exercise. Research uses machine learning to analyze fNIRS data, offering new insights for personalized exercise prescription in rehabilitation and sports medicine.

Originally reported by ClinicalTrials.gov

References

  1. 1.Lincoln University College. (2024). Lower limb muscle strength and power predict exercise-induced prefrontal hemodynamic response: An interpretable machine learning study using fNIRS data. ClinicalTrials.gov. NCT07575802. https://clinicaltrials.gov/study/NCT07575802
  2. 2.Reardon, C., Happ, A., Stieger, J., & Makeig, S. (2023). The neurovascular coupling response to exercise: A systematic review. Neuroscience & Biobehavioral Reviews, 145, 105142. https://doi.org/10.1016/j.neubiorev.2023.105142
  3. 3.Herold, F., Wiegel, P., Scholkmann, F., & Müller, N. G. (2022). Functional near-infrared spectroscopy in movement science: A systematic review on cortical activity in postural and walking tasks. Neurophotonics, 9(1), 010901. https://doi.org/10.1117/1.NPh.9.1.010901
  4. 4.Northey, J. M., Cherbuin, N., Pumpa, K. L., Smee, D. J., & Rattray, B. (2018). Exercise interventions for cognitive function in adults older than 50: A systematic review with meta-analysis. British Journal of Sports Medicine, 52(3), 154-160. https://doi.org/10.1136/bjsports-2016-096587
  5. 5.Mandolesi, L., Polverino, A., Montuori, S., Foti, F., Ferraioli, G., Sorrentino, P., & Sorrentino, G. (2018). Effects of physical exercise on cognitive functioning and wellbeing: Biological and psychological benefits. Frontiers in Psychology, 9, 509. https://doi.org/10.3389/fpsyg.2018.00509
Share:XLinkedIn
2

247 Health News Editorial

247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.

This content is for educational purposes for healthcare professionals only and does not constitute clinical advice. Clinical decisions should be based on individual patient assessment, current guidelines, and appropriate specialist consultation. Editorial Standards · Privacy Policy · Terms of Service