Completed Study Reveals Lower Limb Strength Predicts Brain Oxygenation During Exercise — New Insights for Rehabilitation and Sports Medicine
247 Health News Editorial
·14 May 2026
·4 min read
·clinical-trialsCompleted study of 256 participants reveals lower limb muscle strength can predict brain oxygenation patterns during exercise. Research uses machine learning to analyze fNIRS data, offering new insights for personalized exercise prescription in rehabilitation and sports medicine.
Originally reported by ClinicalTrials.gov
References
- 1.Lincoln University College. (2024). Lower limb muscle strength and power predict exercise-induced prefrontal hemodynamic response: An interpretable machine learning study using fNIRS data. ClinicalTrials.gov. NCT07575802. https://clinicaltrials.gov/study/NCT07575802
- 2.Reardon, C., Happ, A., Stieger, J., & Makeig, S. (2023). The neurovascular coupling response to exercise: A systematic review. Neuroscience & Biobehavioral Reviews, 145, 105142. https://doi.org/10.1016/j.neubiorev.2023.105142
- 3.Herold, F., Wiegel, P., Scholkmann, F., & Müller, N. G. (2022). Functional near-infrared spectroscopy in movement science: A systematic review on cortical activity in postural and walking tasks. Neurophotonics, 9(1), 010901. https://doi.org/10.1117/1.NPh.9.1.010901
- 4.Northey, J. M., Cherbuin, N., Pumpa, K. L., Smee, D. J., & Rattray, B. (2018). Exercise interventions for cognitive function in adults older than 50: A systematic review with meta-analysis. British Journal of Sports Medicine, 52(3), 154-160. https://doi.org/10.1136/bjsports-2016-096587
- 5.Mandolesi, L., Polverino, A., Montuori, S., Foti, F., Ferraioli, G., Sorrentino, P., & Sorrentino, G. (2018). Effects of physical exercise on cognitive functioning and wellbeing: Biological and psychological benefits. Frontiers in Psychology, 9, 509. https://doi.org/10.3389/fpsyg.2018.00509
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