Health Technology/clinical-trials

Completed Study Compares AI Clinical Decision Support Tools: OpenEvidence vs GPT-4 Performance Among Internal Medicine Physicians

247 Health News Editorial

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11 Apr 2026

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3 min read

·clinical-trials

A completed study comparing OpenEvidence and GPT-4 AI platforms found differences in clinical reasoning support among 27 internal medicine physicians. Results could guide healthcare institutions in selecting optimal AI clinical decision support tools.

Originally reported by ClinicalTrials.gov

References

  1. 1.Montefiore Medical Center. (2024). Comparing Clinical Key AI and GPT-4 for diagnostic reasoning and management decisions [Clinical trial registration NCT07037940]. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07037940
  2. 2.Sutton, R. T., Pincock, D., Baumgart, D. C., Sadowski, D. C., Fedorak, R. N., & Kroeker, K. I. (2020). An overview of clinical decision support systems: benefits, risks, and strategies for success. NPJ Digital Medicine, 3, 17. https://doi.org/10.1038/s41746-020-0221-y
  3. 3.Rajpurkar, P., Chen, E., Banerjee, O., & Topol, E. J. (2022). AI in health and medicine. Nature Medicine, 28(1), 31-38. https://doi.org/10.1038/s41591-021-01614-0
  4. 4.Graber, M. L., Franklin, N., & Gordon, R. (2005). Diagnostic error in internal medicine. Archives of Internal Medicine, 165(13), 1493-1499. https://doi.org/10.1001/archinte.165.13.1493
  5. 5.Shortliffe, E. H., & Sepúlveda, M. J. (2018). Clinical decision support in the era of artificial intelligence. JAMA, 320(21), 2199-2200. https://doi.org/10.1001/jama.2018.17163
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247 Health News Editorial

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