Completed Pilot RCT: IMB-Guided Digital Intervention Boosts HIV Self-Testing and PrEP Uptake in Young Men Who Have Sex with Men
247 Health News Editorial
·9 May 2026
·4 min read
·clinical-trialsA completed US pilot RCT demonstrated that theory-based digital interventions can effectively promote HIV self-testing and PrEP uptake among young men who have sex with men. The study's IMB model approach offers insights for Australian HIV prevention strategies.
Originally reported by ClinicalTrials.gov
References
- 1.Australian Government Department of Health. (2022). Pre-exposure prophylaxis (PrEP) for HIV prevention. Australian Government Health Guidelines. https://www.health.gov.au/topics/sexual-health/sexually-transmissible-infections-stis/hiv/pre-exposure-prophylaxis-prep-for-hiv-prevention
- 2.Bauermeister, J. A., Tingler, R. C., Demers, M., Harper, G. W., Santana, M., & Horvath, K. J. (2017). A multilevel tailored web app-based intervention for linking young men who have sex with men to quality care (Get Connected): Protocol for a randomized controlled trial. JMIR Research Protocols, 6(12), e8444. https://doi.org/10.2196/resprot.8444
- 3.Centers for Disease Control and Prevention. (2021). Preexposure prophylaxis for the prevention of HIV infection in the United States—2021 Update: A clinical practice guideline. CDC Guidelines. https://www.cdc.gov/hiv/pdf/risk/prep/cdc-hiv-prep-guidelines-2021.pdf
- 4.Fisher, J. D., & Fisher, W. A. (2000). Theoretical approaches to individual-level change in HIV risk behavior. In Handbook of HIV prevention (pp. 3-55). Springer. https://doi.org/10.1007/978-1-4615-4137-0_1
- 5.Golub, S. A., Fikslin, R. A., Starbuck, L., & Klein, A. (2018). From efficacy to effectiveness: Facilitating HIV preexposure prophylaxis uptake and adherence among young men who have sex with men and transgender women. AIDS, 32(Suppl 1), S25-S33. https://doi.org/10.1097/QAD.0000000000001701
- 6.Hess, K. L., Hu, X., Lansky, A., Mermin, J., & Hall, H. I. (2017). Lifetime risk of a diagnosis of HIV infection in the United States. Annals of Epidemiology, 27(4), 238-243. https://doi.org/10.1016/j.annepidem.2017.02.003
- 7.Johnson, C. C., Kennedy, C., Fonner, V., Siegfried, N., Figueroa, C., Dalal, S., ... & Baggaley, R. (2017). Examining the effects of HIV self-testing compared to standard HIV testing services: A systematic review and meta-analysis. Journal of the International AIDS Society, 20(1), 21594. https://doi.org/10.7448/IAS.20.1.21594
- 8.Medical College of Wisconsin. (2024). Optimizing an IMB-guided Intervention to Support HIV Self-testing and PrEP Uptake Among YMSM: A Pilot Randomized Controlled Trial. ClinicalTrials.gov. NCT04865341. https://clinicaltrials.gov/study/NCT04865341
- 9.Mustanski, B., Macapagal, K., Thomann, M., Feinstein, B. A., Newcomb, M. E., & Whitton, S. W. (2020). Geographic and individual associations with PrEP stigma: Results from the RADAR cohort of diverse young men who have sex with men and transgender women. AIDS and Behavior, 24(12), 3293-3304. https://doi.org/10.1007/s10461-020-02952-x
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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