Health Technology/clinical-trials

Completed Chinese Trial of 19,697 Children Compares Traditional vs Technology-Enhanced Cardiac Screening — Implications for Australian Paediatric Practice

247 Health News Editorial

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8 Apr 2026

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4 min read

·clinical-trials

A completed Chinese trial of nearly 20,000 children compared traditional physician cardiac screening with technology-enhanced auscultation for detecting congenital heart disease. Results could inform screening protocols globally, including in Australian rural and remote settings.

Originally reported by ClinicalTrials.gov

References

  1. 1.Sun, K. (2024). Efficacy Comparison Between Independent Auscultation by Primary Care Physicians and AI-Assisted Auscultation in Large-scale Screening for Congenital Heart Disease: A Cluster Randomized Controlled Trial in China. ClinicalTrials.gov. NCT06791109. https://clinicaltrials.gov/study/NCT06791109
  2. 2.Hoffman, J. I., & Kaplan, S. (2002). The incidence of congenital heart disease. Journal of the American College of Cardiology, 39(12), 1890-1900. https://doi.org/10.1016/s0735-1097(02)01886-7
  3. 3.van der Linde, D., Konings, E. E., Slager, M. A., Witsenburg, M., Helbing, W. A., Takkenberg, J. J., & Roos-Hesselink, J. W. (2011). Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis. Journal of the American College of Cardiology, 58(21), 2241-2247. https://doi.org/10.1016/j.jacc.2011.08.025
  4. 4.Mahle, W. T., Newburger, J. W., Matherne, G. P., Smith, F. C., Hoke, T. R., Koppel, R., ... & Beekman, R. H. (2009). Role of pulse oximetry in examining newborns for congenital heart disease: a scientific statement from the American Heart Association and American Academy of Pediatrics. Circulation, 120(5), 447-458. https://doi.org/10.1161/CIRCULATIONAHA.109.192576
  5. 5.Warnes, C. A., Liberthson, R., Danielson, G. K., Dore, A., Harris, L., Hoffman, J. I., ... & Webb, G. D. (2001). Task force 1: the changing profile of congenital heart disease in adult life. Journal of the American College of Cardiology, 37(5), 1170-1175. https://doi.org/10.1016/s0735-1097(01)01272-4
  6. 6.Frank, J. E., & Jacobe, K. M. (2011). Evaluation and management of heart murmurs in children. American Family Physician, 84(7), 793-800.
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