Cluster-Randomised Trial Tests Digital Decision Support for Antenatal Care in South Asia — Implications for Global Maternal Health
247 Health News Editorial
·22 May 2026
·3 min read
·clinical-trialsThe mIRA trial evaluates a tablet-based decision support system for improving antenatal care quality in India and Nepal. This cluster-randomised study targets gestational diabetes, pregnancy-induced hypertension, and anaemia detection in primary care settings.
Originally reported by ClinicalTrials.gov
References
- 1.Australian Institute of Health and Welfare. (2023). Maternal deaths in Australia. AIHW. https://www.aihw.gov.au/reports/mothers-babies/maternal-deaths-in-australia
- 2.Curran, G. M., Bauer, M., Mittman, B., Pyne, J. M., & Stetler, C. (2012). Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research. Medical Care, 50(3), 217-226. https://doi.org/10.1097/MLR.0b013e3182408812
- 3.Hemming, K., Haines, T. P., Chilton, P. J., Girling, A. J., & Lilford, R. J. (2015). The stepped wedge cluster randomised trial: rationale, design, analysis, and reporting. BMJ, 350, h391. https://doi.org/10.1136/bmj.h391
- 4.Kaur, J., Kaur, M., & Webster, J. (2023). Prevalence and risk factors of gestational diabetes mellitus in South Asia: A systematic review. Diabetes Research and Clinical Practice, 195, 110234. https://doi.org/10.1016/j.diabres.2023.110234
- 5.Lund, S., Nielsen, B. B., Hemed, M., Boas, I. M., Said, A., Said, K., Makungu, M. H., & Rasch, V. (2014). Mobile phones improve antenatal care attendance in Zanzibar: a cluster randomized controlled trial. BMC Pregnancy and Childbirth, 14, 29. https://doi.org/10.1186/1471-2393-14-29
- 6.Public Health Foundation of India. (2024). A Cluster-randomized Trial of an mHealth Integrated Model of Hypertension, Diabetes and Antenatal Care in Primary Care Settings in India and Nepal. ClinicalTrials.gov. NCT03700034. https://clinicaltrials.gov/study/NCT03700034
- 7.Sharma, B., Giri, G., Christensson, K., Ramkumaran, A., & Johansson, E. (2021). The transition of antenatal care among rural women in Nepal and the role of female community health volunteers. Reproductive Health, 18, 156. https://doi.org/10.1186/s12978-021-01217-y
- 8.Sharma, S., Vik, E. S., Pakrashi, T., & Løset, M. (2021). Antenatal care and maternal health outcomes in South Asia. International Journal of Gynecology & Obstetrics, 153(2), 285-292. https://doi.org/10.1002/ijgo.13567
- 9.World Health Organization. (2023). Trends in maternal mortality 2000 to 2020: estimates by WHO, UNICEF, UNFPA, World Bank Group and UNDESA/Population Division. World Health Organization. https://www.who.int/publications/i/item/9789240068759
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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