BOT-IMPROVE-HF Trial: Digital Remote Monitoring for Heart Failure Medication Optimisation — Early Results Show Promise
247 Health News Editorial
·12 June 2026
·3 min read
·clinical-trialsThe completed BOT-IMPROVE-HF trial investigated whether smartphone-based digital monitoring could improve medication optimisation in heart failure patients post-discharge. Results from this 66-patient study may inform future digital health strategies for heart failure care.
Originally reported by ClinicalTrials.gov
References
- 1.I.M. Sechenov First Moscow State Medical University. (2024). ContriBution of Digital RemOte MoniToring to IMPROVing The Effectiveness of Treatment in Patients With Chronic Heart Failure With Low Ejection Fraction. ClinicalTrials.gov. NCT06304753. https://clinicaltrials.gov/study/NCT06304753
- 2.Savarese, G., Becher, P. M., Lund, L. H., Seferovic, P., Rosano, G. M., & Coats, A. J. (2023). Global burden of heart failure: a comprehensive and updated review of epidemiology. Cardiovascular Research, 119(6), 1218-1229. https://doi.org/10.1093/cvr/cvac013
- 3.Greene, S. J., Butler, J., Albert, N. M., DeVore, A. D., Sharma, P. P., Duffy, C. I., ... & Fonarow, G. C. (2018). Medical therapy for heart failure with reduced ejection fraction: the CHAMP-HF registry. Journal of the American College of Cardiology, 72(4), 351-366. https://doi.org/10.1016/j.jacc.2018.04.014
- 4.McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Böhm, M., ... & Kathrine Skibelund, A. (2021). 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 42(36), 3599-3726. https://doi.org/10.1093/eurheartj/ehab368
- 5.Virani, S. S., Alonso, A., Aparicio, H. J., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., ... & Tsao, C. W. (2021). Heart disease and stroke statistics—2021 update: a report from the American Heart Association. Circulation, 143(8), e254-e743. https://doi.org/10.1161/CIR.0000000000000950
- 6.Komajda, M., Cowie, M. R., Tavazzi, L., Ponikowski, P., Anker, S. D., & Filippatos, G. S. (2017). Physicians' guideline adherence is associated with better prognosis in outpatients with heart failure with reduced ejection fraction: the QUALIFY international registry. European Journal of Heart Failure, 19(11), 1414-1423. https://doi.org/10.1002/ejhf.887
- 7.Dharmarajan, K., Hsieh, A. F., Lin, Z., Bueno, H., Ross, J. S., Horwitz, L. I., ... & Krumholz, H. M. (2013). Diagnoses and timing of 30-day readmissions after hospitalization for heart failure, acute myocardial infarction, or pneumonia. JAMA, 309(4), 355-363. https://doi.org/10.1001/jama.2013.6056
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247 Health News Editorial
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