Health Technology/clinical-trials

BIRTH Study Demonstrates Mobile Health Impact on Neonatal Resuscitation in Resource-Limited Settings — Key Findings for Global Health Practice

247 Health News Editorial

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29 May 2026

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3 min read

·clinical-trials

The completed BIRTH Study demonstrates how mobile health technology can improve neonatal resuscitation practices in resource-limited settings. This cluster-randomized trial of 14,680 participants in the Democratic Republic of the Congo provides crucial evidence for scaling digital health interventions to reduce newborn mortality globally.

Originally reported by ClinicalTrials.gov

References

  1. 1.University of North Carolina, Chapel Hill. (2024). Bedside Improvement of Resuscitation Through mHealth Feedback (BIRTH Study). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT05963516
  2. 2.Wyckoff, M. H., Wyllie, J., Aziz, K., de Almeida, M. F., Fabres, J., Fawke, J., Guinsburg, R., Hosono, S., Isayama, T., Kapadia, V. S., Kim, H. S., Liley, H. G., McKinlay, C. J. D., Mildenhall, L., Perlman, J. M., Rabi, Y., Roehr, C. C., Schmölzer, G. M., Szyld, E., ... Zaichkin, J. (2022). Neonatal Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science. Circulation, 142(16_suppl_1), S185-S221. https://doi.org/10.1161/CIR.0000000000001017
  3. 3.Ersdal, H. L., Mduma, E., Svensen, E., & Perlman, J. M. (2012). Early initiation of basic resuscitation interventions including face mask ventilation may reduce birth asphyxia related mortality in low-income countries. Resuscitation, 83(7), 869-873. https://doi.org/10.1016/j.resuscitation.2011.11.015
  4. 4.Campbell, M. K., Piaggio, G., Elbourne, D. R., & Altman, D. G. (2012). Consort 2010 statement: extension to cluster randomised trials. BMJ, 345, e5661. https://doi.org/10.1136/bmj.e5661
  5. 5.Lawn, J. E., Blencowe, H., Oza, S., You, D., Lee, A. C., Waiswa, P., Lalli, M., Bhutta, Z., Barros, A. J., Christian, P., Mathers, C., & Cousens, S. N. (2014). Every Newborn: progress, priorities, and potential beyond survival. The Lancet, 384(9938), 189-205. https://doi.org/10.1016/S0140-6736(14)60496-7
  6. 6.UNICEF. (2023). Levels and Trends in Child Mortality: Report 2023. UNICEF Data. https://data.unicef.org/topic/child-survival/neonatal-mortality/
  7. 7.Lee, A. C., Cousens, S., Wall, S. N., Niermeyer, S., Darmstadt, G. L., Carlo, W. A., Keenan, W. J., Bhutta, Z. A., Gill, C., & Lawn, J. E. (2011). Neonatal resuscitation and immediate newborn assessment and stimulation for the prevention of neonatal deaths. International Journal of Epidemiology, 40(2), 426-443. https://doi.org/10.1093/ije/dyr054
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247 Health News Editorial

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