AI Drug Design Speeds Protein Creation, But Clinical Testing Remains Bottleneck

References

1. 1.Trang, B. (2026, May 26). An AI biotech CEO sets the record straight on AI drug development hype. STAT News. https://www.statnews.com/2026/05/26/ai-biotech-bighat-biosciences-ceo-on-ai-drug-development-hype/
2. 2.Paul, S. M., Mytelka, D. S., Dunwiddie, C. T., Persinger, C. C., Munos, B. H., Lindborg, S. R., & Schacht, A. L. (2010). How to improve R&D productivity: the pharmaceutical industry's grand challenge. Nature Reviews Drug Discovery, 9(3), 203-214. https://doi.org/10.1038/nrd3078
3. 3.Kaplon, H., Chenoweth, A., Crescioli, S., & Reichert, J. M. (2022). Antibodies to watch in 2022. mAbs, 14(1), 2014296. https://doi.org/10.1080/19420862.2021.2014296
4. 4.Lu, R. M., Hwang, Y. C., Liu, I. J., Lee, C. C., Tsai, H. Z., Li, H. J., & Wu, H. C. (2020). Development of therapeutic antibodies for the treatment of diseases. Journal of Biomedical Science, 27(1), 1-30. https://doi.org/10.1186/s12929-019-0592-z
5. 5.Kesselheim, A. S., Hwang, T. J., & Franklin, J. M. (2015). Two decades of new drug development for central nervous system disorders. Nature Reviews Drug Discovery, 14(12), 815-816. https://doi.org/10.1038/nrd4793
6. 6.Ekins, S., Puhl, A. C., Zorn, K. M., Lane, T. R., Russo, D. P., Klein, J. J., ... & Clark, A. M. (2019). Exploiting machine learning for end-to-end drug discovery and development. Nature Materials, 18(5), 435-441. https://doi.org/10.1038/s41563-019-0338-z
7. 7.Mak, K. K., & Pichika, M. R. (2019). Artificial intelligence in drug development: present status and future prospects. Drug Discovery Today, 24(3), 773-780. https://doi.org/10.1016/j.drudis.2018.11.014
8. 8.Fleming, N. (2018). How artificial intelligence is changing drug discovery. Nature, 557(7706), S55-S57. https://doi.org/10.1038/d41586-018-05267-x