Health Technology/clinical-trials

AI-Assisted Echocardiography Trial Targets Rheumatic Heart Disease Screening in Uganda — Implications for Global Health Programs

247 Health News Editorial

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28 May 2026

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3 min read

·clinical-trials

A pragmatic trial in Uganda evaluates AI-assisted echocardiography for rheumatic heart disease screening by nurse practitioners. The RADAR system aims to democratise early detection in resource-limited settings where specialist cardiac expertise is scarce.

Originally reported by ClinicalTrials.gov

References

  1. 1.Children's Hospital Medical Center, Cincinnati. (2024). Artificial Intelligence to Scale Early Rheumatic Heart Disease Detection. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07599956
  2. 2.Beaton, A., Okello, E., Lwabi, P., Mondo, C., McCarter, R., & Sable, C. (2012). Echocardiography screening for rheumatic heart disease in Ugandan schoolchildren. Circulation, 125(25), 3127-3132. https://doi.org/10.1161/CIRCULATIONAHA.112.096644
  3. 3.Watkins, D. A., Johnson, C. O., Colquhoun, S. M., Karthikeyan, G., Beaton, A., Bukhman, G., ... & Roth, G. A. (2017). Global, regional, and national burden of rheumatic heart disease, 1990–2015. New England Journal of Medicine, 377(8), 713-722. https://doi.org/10.1056/NEJMoa1603693
  4. 4.Zühlke, L., Engel, M. E., Karthikeyan, G., Rangarajan, S., Mackie, P., Cupido, B., ... & Mayosi, B. M. (2016). Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry. European Heart Journal, 37(13), 1115-1122. https://doi.org/10.1093/eurheartj/ehv711
  5. 5.Nascimento, B. R., Beaton, A. Z., Nunes, M. C. P., Diamantino, A. C., Carmo, G. A. L., Oliveira, K. K. B., ... & Ribeiro, A. L. P. (2020). Echocardiographic prevalence of rheumatic heart disease in Brazilian schoolchildren: data from the PROVAR study. International Journal of Cardiology, 299, 78-84. https://doi.org/10.1016/j.ijcard.2019.10.007
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