Health Technology/clinical-trials

Adaptive Trial Launches: Peer-Supported Mobile Health vs Self-Management for Psychological Distress in Primary Care Veterans — What Clinicians Need to Know

247 Health News Editorial

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23 July 2026

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5 min read

·clinical-trials

A new adaptive trial from the VA Office of Research and Development is testing whether peer specialist-supported mobile health applications can reduce psychological distress in veterans seen in primary care — and how much peer support is actually needed to drive clinical benefit. The SMART design trial will enrol 384 veterans across three US sites, with results anticipated by 2029.

Originally reported by ClinicalTrials.gov

References

  1. 1.VA Office of Research and Development. (2025). Testing an adaptive intervention for peer-supported mobile health for primary care veterans with psychological distress (NCT07507747). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07507747
  2. 2.Chinman, M., George, P., Dougherty, R. H., Daniels, A. S., Ghose, S. S., Swift, A., & Delphin-Rittmon, M. E. (2014). Peer support services for individuals with serious mental illnesses: Assessing the evidence. Psychiatric Services, 65(4), 429–441. https://doi.org/10.1176/appi.ps.201300244
  3. 3.Almiral, D., Witkiewitz, K., & Murphy, S. A. (2014). Introduction to the special section on adaptive interventions and SMART designs in substance use research. Journal of Studies on Alcohol and Drugs, 75(4), 529–531. https://doi.org/10.15288/jsad.2014.75.529
  4. 4.Lovibond, S. H., & Lovibond, P. F. (1995). Manual for the Depression Anxiety Stress Scales (2nd ed.). Psychology Foundation of Australia.
  5. 5.Substance Abuse and Mental Health Services Administration. (2023). Behavioral health among U.S. active duty military personnel, veterans, and military families. SAMHSA. https://www.samhsa.gov/data/report/behavioral-health-among-us-active-duty-military-personnel-veterans-and-military-families
  6. 6.Torous, J., Lipschitz, J., Ng, M., & Firth, J. (2020). Dropout rates in clinical trials of smartphone apps for depressive symptoms: A systematic review and meta-analysis. Journal of Affective Disorders, 263, 413–419. https://doi.org/10.1016/j.jad.2019.11.167
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247 Health News Editorial

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